Simulation Based Process Optimization and Trouble Shooting
- Computational Modelling on Material compatibility, Solvent Screening, Reaction Feasibility, Crystallization, Impurities Assessment & Rejection, Toxicology studies, Stability Studies.
- Packaging material selections for a given formulation.
- Absorption Modelling, Solubility Modelling, Skin Permeability Modelling.
- IVIVC (in vitro in vivo correlation) predictive modelling.
- Identification of Critical Process Parameters (CPP) , Critical Material Attributes (CMA), Critical Quality Attributes (CQA) for manufacturing needs.
- Powder discharge status and result assessment of the powder particles in chosen blending and mixer.
- Blender/Mixer size, type and geometry assessment for an agreed yield.
- Assessment of flow during tableting and appropriate tableting speed setting, and to address homogeneity & consistency issues during tableting.
- Analytics & Statistics of powder flow during the experimental process.